High-temporal-resolution recordings that resolve single-neuron and population dynamics during natural behavior.

Longitudinal imaging of large identified neural populations in behaving animals across learning, memory, and disease.

Cellular and synaptic measurements in controlled preparations to connect circuit mechanisms with in vivo function.

Population-level measurement of neural and neuromodulatory signals during task performance and behavioral state changes.

Temporally precise manipulation of defined neural populations to test causal circuit mechanisms.

Selective pathway and cell-type manipulation over longer timescales to probe behavior and circuit function.

Input mapping methods that reveal the circuit architecture of memory and navigation systems.

Genetic tools for cell-type-specific experiments and for studying disease-related circuit dysfunction.

Mechanistic models grounded in experimental data to interpret results and generate testable predictions.